How does ivermectin reduce allergic skin inflammation?

Ivermectin cream for humans is primarily known for its anti-parasitic properties, but it also has anti-inflammatory effects, which may contribute to reducing allergic skin inflammation in certain conditions. While ivermectin is not typically used to treat allergies or allergic reactions, it can reduce inflammation through several mechanisms.

In cases where allergic-like inflammation is caused or exacerbated by parasitic infections (such as scabies or Demodex mites), ivermectin's ability to target and eliminate these parasites can indirectly reduce inflammation.